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Dera Ismail Khan, often abbreviated to D.I. Khan, is a city in Khyber Pakhtunkhwa Province, Pakistan. It is situated on the west bank of the Indus River, about 300 kilometers (190 mi) south of the provincial capital Peshawar, and 230 kilometers (140 mi) northwest of Multan, Punjab. The city is the capital of the district and tehsil of the same name. The total population of the city was 217,457 in the 2017 Census, making it the 37th Largest city in Pakistan and largest city in the southern part of Khyber Pakhtunkhwa.
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The climate here is "desert." There is virtually no rainfall during the year. This climate is considered to be BWh according to the Koppen-Geiger climate classification. The average annual temperature in Dera Ismail Khan is 24.5 °C. The average annual rainfall is 249 mm.